Figure 3.
Intracellular Cisplatin Content Is Increased with miR-31 Reintroduction
ICP-MS analysis of NCI-H2452 and P31-transfected cell lines treated with 50 μM cisplatin for 24 hr. There is a significant (p = 0.0112) increase in the levels of platinum in NCI-H2452 miR-31 cells compared to miR-VC equivalent, but there is no change in overall platinum levels with miR-31 suppression (n = 3). Data are presented as the mean ± SEM. *p < 0.05; **p < 0.01; ns, not significant.