Table 3.
Receiver operating characteristics and Bayesian analysis of venous thromboembolism predictive value of glycemic parameters
| Fasting blood glucose | Fasting insulin | HOMA | HbA1c | |
| AUC (SE) | 0.636 (0.06) | 0.630 (0.05) | 0.647 (0.05) | 0.574 (0.06) |
| 95%CI | 0.582-0.687 | 0.576-0.681 | 0.593-0.697 | 0.519-0.627 |
| Criterion1 | 103 mg/dL | 12 μIU/mL | 2.6 | 6.0% |
| Sensitivity | 75% | 75% | 81% | 59% |
| Specificity | 65% | 51% | 48% | 63% |
| PPV | 18% | 14% | 14% | 14% |
| NPV | 96% | 95% | 96% | 94% |
| +LR (CI) | 2.12 (1.54-2.57) | 1.54 (1.13-1.85) | 1.56 (1.19-1.81) | 1.60 (1.07-2.13) |
| -LR (CI) | 0.39 (0.19-0.68) | 0.49 (0.23-0.87) | 0. 39 (0.16-0.78) | 0.65 (0.38-0.96) |
| P value2 | 0.0135 | 0.0128 | 0.0045 | 0.1989 |
1
Corresponding with highest Youden index;
2
Significance level P (Area = 0.5). AUC: Area under the curve; PPV: Positive predictive value; NPV: Negative predictive value; +LR: Positive likelihood ratio; -LR: Negative likelihood ratio.