Fig. 3.
Superposition of JNJ-53718678, BMS433771, and JNJ-49153390 binding modes. a, b Top a and b side view overlay for prefusion RSV F bound to inhibitors. RSV F is shown in cartoon representation with the three identical protomers each shown in a different color (FA, green; FB, pink; and FC, tan) and hydrophobic side chains are shown with transparent molecular surfaces. Inhibitors are shown as ball-and-stick representations with carbon atoms colored in grey, yellow, and cyan for JNJ-537118678, JNJ-49153390, and BMS-433771, respectively. Nitrogen atoms are colored in blue, oxygen atoms in red, chlorine atom in dark green, fluorine atoms in light blue, bromine atom in dark red, and sulfur atoms in orange