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. 2017 Jul 31;7:6966. doi: 10.1038/s41598-017-07294-6

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Time latencies needed for experimental rats to find the escape platform in the two-choice visual discrimination apparatus. The 4 experimental groups were sham operated rats (CTL), sham operated rats treated with hypothermia (CTL HYP), IONC operated rats (in both eyes), and IONC operated animals (in both eyes) treated with hypothermia (IONC HYP). Bars represent the mean ± SD of all samples (n = 10 animals per group). Asterisks represent statistically significant differences. *p < 0.05; ***p < 0.001; comparing IONC versus IONC HYP.