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. 2017 Jul 31;7:6897. doi: 10.1038/s41598-017-07172-1

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Representative flow cytometry dot plot showing CCR2 expression on Treg cells in peripheral blood (PB) and pancreatic lymph nodes (PLN) of a patient with T1D (left panel) and data collected in 3 patients with T1D (right panel). (B) Correlation analysis between percentages of CCR2⁺ cells in Treg cells (left panel) and Tconv cells (right panel) measured by flow cytometry and miR-125a-5p expression values measured as 2^−dCT. Spearman R test was used.