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. 2017 Jul 31;7:6889. doi: 10.1038/s41598-017-05930-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Ethylene and 8-isoprostane release during human endotoxemia. (a) Time course of ethylene levels in breath of healthy volunteers after intravenous administration of a single dose of LPS at t = 0. (b) Time course of 8-isoprostane levels as determined by EIA in serum samples of healthy volunteers after intravenous administration of a single dose of LPS (present study, n = 8) or phosphate buffered saline (PBS) (previous study, n = 6) at t = 0. Data points show median with interquartile range, asterisks indicate significance compared to baseline (t = −30 for ethylene, t = 0/−50 for 8-isoprostane PBS/LPS).