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AIE Chromatograms of 260 nm of Stereo-Defined and Random Mixture LNA PS Oligonucleotides
(A) LNA 8-mer (5′-CACACTCC-3′). S and R denotes all-Sp and all-Rp 8-mers, respectively. The random mixture (128 diastereoisomers) was partly resolved between the peaks of “S” and “R.” (B) LNA 7-gapmer (5′-AT-gta-GC-3′). S and R denotes all-Sp and all-Rp 7-gapmers, respectively. The random mixture (64 diastereoisomers) elutes as a broad band between the two peaks.
