Table 3. Toxicity interval probabilities for all prespecified dose levels after one patient has been treated with 5 mg.
Probability of toxicity rate in |
||||
---|---|---|---|---|
Dose (mg) | (0–0.16) Undertoxicity | (0.16–0.33) Target toxicity | (0.33–1) Overtoxicity | Mean toxicity rate |
0.2 | 0.889 | 0.065 | 0.046 | 0.056 |
0.5 | 0.860 | 0.075 | 0.065 | 0.071 |
1 | 0.828 | 0.089 | 0.083 | 0.086 |
2.5 | 0.770 | 0.115 | 0.115 | 0.112 |
5 | 0.717 | 0.128 | 0.155 | 0.140 |
10 | 0.649 | 0.144 | 0.207 | 0.177 |
20 | 0.559 | 0.163 | 0.278 | 0.228 |
40 | 0.439 | 0.186 | 0.374 | 0.300 |
80 | 0.301 | 0.179 | 0.520 | 0.403 |
120 | 0.231 | 0.167 | 0.601 | 0.473 |
Numbers in bold indicate safe, and those in italics indicate unsafe.