TABLE 1.
Inhibition Constant (Ki) Values of RYM1 for Recombinant Human MMP-2, -7, -9, -12, and -13
| Protease | Ki (nM) |
| rhMMP-2 | 10.4 ± 0.0 |
| rhMMP-7 | 33.2 ± 5.0 |
| rhMMP-9 | 17.9 ± 8.0 |
| rhMMP-12 | 2.2 ± 0.5 |
| rhMMP-13 | 16.9 ± 2.7 |
rh = recombinant human.
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