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Coverage by Nanopore reads from DNA of M. tb H37Rv (a), M. tb strain C (b) and Illumina-sequenced long-fragment-enriched M. tb H37Rv (c) and M. tb strain C (d), shows a region (886 000–893 000) of high coverage in both Nanopore and Illumina experiments. Nanopore reads were aligned with BLASR, Illumina reads with Bowtie, visualised in IGV. Maximum read depth, as determined by IGV, is 17 (a), 22 (b), 331 (c) and 277 (d).
