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. 2017 Jun 6;7(6):e1147. doi: 10.1038/tp.2017.124

Table 2. PET/SPECT GABAA/BDZ receptor availability data sets: clinical characteristics of the samples.

First author Year Patient group Sample size
SCZ %M SCZ age mean %AP %BZ PANSS DOI
      C SCZ            
Busatto67 1997 SCZ 12 15 93 29 60 NR NR 6.5
Verhoeff70 1999 SCZ 24 25 100 41 80 0 NR NR
Abi-Dargham71 1999 SCZ 16 16 100 44 69 0 NR NR
Asai72 2008 SCZ 11 12 55 33 0 0 90.4 NR
Lee74 2013 SCZ 18 17 47 29 100 0 60.5 4.1
Kang73 2014 CHR 15 11 66 19 18 0 NR
Frankle75 2015 SCZ 22 17 65 28 0 NR 83 NR

Abbreviations: %AP, percentage of SCZ group currently taking antipsychotic medication; %BZ, percentage of SCZ group currently taking benzodiazepine or anticonvulsant medication; C, control; CHR, clinical high risk; DOI, mean duration of illness in years; %M, percentage of male in SCZ sample; NR, not reported; PANSS, Positive and Negative Syndrome Scale mean total symptom score; SCZ, schizophrenia. Age is expressed in years, mean; regional effect sizes are provided in Figure 2.