Table 2.

Multivariable Analyses: Predictors of Hospital Mortality in Patients with a Primary Diagnosis of TTP (only subjects who underwent TPE are included in this analysis.)

Predictor variables in the multivariable model	Odds Ratio Estimates	95% Wald Confidence Limits		P-value
Platelet Transfusion	2.19	1.19	4.05	<0.05
Intracranial Hemorrhage	6.05	1.58	23.24	<0.01
Arterial Thrombosis	6.73	1.11	40.91	<0.05
Myocardial Infarction	2.32	1.16	4.63	<0.05
Ischemic Stroke	2.42	1.17	5.01	<0.05
Age (>=60 years)	3.47	2.14	5.63	<.0001
Renal Failure	2.56	1.46	4.47	<0.01
Non Central Nervous System Bleeding**	1.21	0.62	2.38	0.57
Gender**	1.10	0.67	1.79	0.71
Race (Caucasians versus African Americans)**	1.47	0.88	2.45	0.14

^*Area under receiver operating characteristic curve: 78.6%

^**Significant factors are in boldface type. Model is also adjusted for Gender, Non Central Nervous System Bleeding and Race (Caucasian versus African American)

^***Good model calibration and fit per the hosmer-lemeshaw goodness-of-fit test