Fig. 5.

Relative risks for treatment failure following the decentralized care of multidrug-resistant tuberculosis – compared with centralized care, 2008–2013

CI: confidence interval; df: degrees of freedom; RR: relative risk.

Notes: This forest plot summarizes the main results of a random-effects meta-analysis of the data from three studies. Treatment failure was the outcome recorded when – because of a lack of conversion by the end of the intensive phase, bacteriological reversion in the continuation phase after conversion to negative, evidence of additional acquired resistance to fluoroquinolones or second-line injectable drugs or adverse drug reactions – treatment was terminated or there was a need for a permanent regimen change involving at least two anti-tuberculosis drugs.¹¹