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Chestnut leaf extract promoted the cytoplasmic levels of apoptosis-associated proteins in MCF-7-derived CSCs. (A–C) Immunoblot images and quantified data for Bax and Bcl-2 (A,B), cytochrome C (B), and cleaved PARP (C). Taxol, paclitaxel (10 nM); CC, Castanea crenata leaf extract (25 or 50 μg/mL). N = 3; error bars, mean ± SEM. Values not sharing common letter on bar indicate statistically significant difference from each other (p < 0.05).
