Table 1.

Overexpression of CAPΔSoHo attenuates insulin-stimulated glucose uptake

	LacZ	CAP	CAPΔSH3	CAPΔSoHo
Basal	1	1.19  ± 0.2	0.78  ± 0.11	0.86  ± 0.09
Insulin	8.87  ± 0.77	8.51  ± 0.61	4.76  ± 0.46**	4.88  ± 0.44**

Differentiated 3T3-L1 adipocytes were transfected with LacZ, CAP, CAPΔSH3, and CAPΔSoHo. The cells were then either left untreated or stimulated with 100 nM insulin for 30 min. The rate of [¹⁴C]2-deoxyglucose uptake was determined. Results are expressed as fold stimulation over the LacZ basal control, and are the mean of three independent experiments ± standard error from individual experiments performed in triplicate with transfection efficiency about 50%. 

^**, Significant difference, P < 0.01.