Table 2.
Number of deaths, crude and age-standardized mortality rates (per 100,000 inhabitants) [95% confidence interval] due to viral hepatitis according to the macro-regions in Brazil from 2008 to 2014
| Region | Hepatitis A | Hepatitis B | Hepatitis C | Hepatitis Delta | Other hepatitis | All |
|---|---|---|---|---|---|---|
| North | ||||||
| Deaths (n) | 59 | 842 | 1071 | 212 | 396 | 2492 |
| Crude MR | 0.052 | 0.745 | 0.948 | 0.196 | 0.350 | 2.205 |
| Age-st-MR [95% CI] | 0.066 | 0.986 | 1.458 | 0.220 | 0.449 | 3.062 |
| [0.049–0.087] | [0.918–1.058] | [1.370–1.550] | [0.190–0.253] | [0.403–0.498] | [2.938–3.189] | |
| Northeast | ||||||
| Deaths (n) | 141 | 930 | 2506 | 30 | 617 | 4153 |
| Crude MR | 0.037 | 0.245 | 0.661 | 0.008 | 0.163 | 1.095 |
| Age-st-MR [95% CI] | 0.039 [0.036–0.046] |
0.278 [0.261–0.297] |
0.780 [0.750–0.812] |
0.009 [0.006–0.013] |
0.176 [0.163–0.191] |
1.261 [1.223–1.301] |
| Southeast | ||||||
| Deaths (n) | 139 | 2900 | 14,111 | 78 | 1226 | 18,146 |
| Crude MR | 0.024 | 0.506 | 2.460 | 0.014 | 0.214 | 3.164 |
| Age-st-MR [95% CI] | 0.024 | 0.486 | 2.367 | 0.013 | 0.207 | 3.045 |
| [0.020–0.028] | [0.468–0.504] | [2.328–2.406] | [0.010–0.016] | [0.195–0.219] | [3.001–3.090] | |
| South | ||||||
| Deaths (n) | 46 | 1285 | 6564 | 40 | 471 | 8281 |
| Crude MR | 0.024 | 0.657 | 3.354 | 0.020 | 0.241 | 4.231 |
| Age-st- MR [95% CI] | 0.023 | 0.621 | 3.163 | 0.019 | 0.230 | 3.997 |
| [0.017–0.031] | [0.588–0.657] | [3.087–3.241] | [0.014–0.026] | [0.210–0.252] | [3.911–4.085] | |
| Central-West | ||||||
| Deaths (n) | 31 | 592 | 1131 | 13 | 187 | 1906 |
| Crude MR | 0.031 | 0.589 | 1.125 | 0.016 | 0.186 | 1.896 |
| Age-st-MR [95% CI] | 0.035 | 0.662 | 1.284 | 0.018 | 0.208 | 2.151 |
| [0.024–0.050] | [0.609–0.718] | [1.209–1.362] | [0.009–0.031] | [0.179–0.241] | [2.054–2.251] | |
| Brazil | ||||||
| Deaths (n) | 416 | 6549 | 25,383 | 373 | 2897 | 34,978 |
| Crude MR | 0.031 | 0.481 | 1.864 | 0.028 | 0.213 | 2.568 |
| Age-st-MR [95% CI] | 0.032 | 0.500 | 1.964 | 0.028 | 0.220 | 2.695 |
| [0.029–0.035] | [0.488–0.512] | [1.940–1.989] | [0.025–0.031] | [0.212–0.229] | [2.667–2.724] | |
Mean population per year (ratio between total population from 2008 to 2014 and 7 years; expressed in millions inhabitants): North =16,145; Northeast = 54,173; Southeast = 81,931; South = 27,956; Central-West = 14.360 and Brazil = 194.567. Crude mortality rate = number of death / mean population * 7 (number of years). Age-st-MR, age-standardized mortality rate; MR, mortality rate. N = 552 patients had co-infection (more than one viral hepatitis ICD-10 codes in their death certificate: HAV/HBV (n = 13); HAV/HCV (n = 7); HBV/HCV (n = 518); HCV/HDV (n = 8); HAV/HBV/HCV (n = 3); HBV/HCV/others viral hepatitis (n = 3). In patients with missing age (n = 10), it was not possible to calculate adjusted-mortality rate