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. 2017 Jul 31;17:527. doi: 10.1186/s12879-017-2619-y

Table 2.

Number of deaths, crude and age-standardized mortality rates (per 100,000 inhabitants) [95% confidence interval] due to viral hepatitis according to the macro-regions in Brazil from 2008 to 2014

Region Hepatitis A Hepatitis B Hepatitis C Hepatitis Delta Other hepatitis All
North
 Deaths (n) 59 842 1071 212 396 2492
 Crude MR 0.052 0.745 0.948 0.196 0.350 2.205
 Age-st-MR [95% CI] 0.066 0.986 1.458 0.220 0.449 3.062
[0.049–0.087] [0.918–1.058] [1.370–1.550] [0.190–0.253] [0.403–0.498] [2.938–3.189]
Northeast
 Deaths (n) 141 930 2506 30 617 4153
 Crude MR 0.037 0.245 0.661 0.008 0.163 1.095
 Age-st-MR [95% CI] 0.039
[0.036–0.046]
0.278
[0.261–0.297]
0.780
[0.750–0.812]
0.009
[0.006–0.013]
0.176
[0.163–0.191]
1.261
[1.223–1.301]
Southeast
 Deaths (n) 139 2900 14,111 78 1226 18,146
 Crude MR 0.024 0.506 2.460 0.014 0.214 3.164
 Age-st-MR [95% CI] 0.024 0.486 2.367 0.013 0.207 3.045
[0.020–0.028] [0.468–0.504] [2.328–2.406] [0.010–0.016] [0.195–0.219] [3.001–3.090]
South
 Deaths (n) 46 1285 6564 40 471 8281
 Crude MR 0.024 0.657 3.354 0.020 0.241 4.231
 Age-st- MR [95% CI] 0.023 0.621 3.163 0.019 0.230 3.997
[0.017–0.031] [0.588–0.657] [3.087–3.241] [0.014–0.026] [0.210–0.252] [3.911–4.085]
Central-West
 Deaths (n) 31 592 1131 13 187 1906
 Crude MR 0.031 0.589 1.125 0.016 0.186 1.896
 Age-st-MR [95% CI] 0.035 0.662 1.284 0.018 0.208 2.151
[0.024–0.050] [0.609–0.718] [1.209–1.362] [0.009–0.031] [0.179–0.241] [2.054–2.251]
Brazil
 Deaths (n) 416 6549 25,383 373 2897 34,978
 Crude MR 0.031 0.481 1.864 0.028 0.213 2.568
Age-st-MR [95% CI] 0.032 0.500 1.964 0.028 0.220 2.695
[0.029–0.035] [0.488–0.512] [1.940–1.989] [0.025–0.031] [0.212–0.229] [2.667–2.724]

Mean population per year (ratio between total population from 2008 to 2014 and 7 years; expressed in millions inhabitants): North =16,145; Northeast = 54,173; Southeast = 81,931; South = 27,956; Central-West = 14.360 and Brazil = 194.567. Crude mortality rate = number of death / mean population * 7 (number of years). Age-st-MR, age-standardized mortality rate; MR, mortality rate. N = 552 patients had co-infection (more than one viral hepatitis ICD-10 codes in their death certificate: HAV/HBV (n = 13); HAV/HCV (n = 7); HBV/HCV (n = 518); HCV/HDV (n = 8); HAV/HBV/HCV (n = 3); HBV/HCV/others viral hepatitis (n = 3). In patients with missing age (n = 10), it was not possible to calculate adjusted-mortality rate