Table 4.
Summary statistics by level of dependence
| Level | Number of Patients (%Total Sample) | MMSE Mean (95% CI) |
ZBI Mean (95% CI) |
NPI Mean (95% CI) |
EQ-5D (Proxy-Reported) Mean (95% CI) |
Caregiver Time/Month (hr) Mean (95% CI) |
Patient Medical Costs (Monthly) (€) Mean (95% CI) |
Total Societal Costs (Monthly) (€) Mean (95% CI) |
|---|---|---|---|---|---|---|---|---|
| 0* | 10 (0.7%) | 23.3 (21.8 – 24.8) | 12.0 (8.4 – 15.6) | 4.1 (−0.1 – 8.3) | 0.80 (0.62 – 0.98) | 8.6 (−2.5 – 19.7) | 1179 (−1038 – 3395) | 1437 (−1036 – 3910) |
| 1 | 35 (2%) | 23.2 | 15.0 | 3.7 | 0.80 | 37.5 | 295 | 881 |
| (22.2 – 24.2) | (12.4 – 17.7) | (2.7 – 4.8) | (0.76 – 0.84) | (19.5 – 55.6) | (96 – 493) | (559 – 1204) | ||
| 2 | 443 (30%) | 20.8 | 22.1 | 9.2 | 0.75 | 74.2 | 311 | 1091 |
| (20.5 – 21.2) | (20.9 – 23.3) | (8.3 – 10.1) | (0.73 – 0.77) | (64.2 – 84.2) | (227 – 395) | (969 – 1212) | ||
| 3 | 382 (26%) | 18.3 | 30.6 | 14.5 | 0.67 | 177.5 | 353 | 1762 |
| (17.8 – 18.8) | (29.1 – 32.1) | (13.2 – 15.9) | (0.64 – 0.69) | (159.7 – 195.3) | (267 – 439) | (1577 – 1946) | ||
| 4 | 516 (34%) | 14.8 | 33.8 | 19.0 | 0.53 | 276.0 | 412 | 2685 |
| (14.2 – 15.3) | (32.6 – 35.1) | (17.6 – 20.4) | (0.50 – 0.56) | (259.1 – 292.8) | (307 – 516) | (2455 – 2915) | ||
| 5 | 111 (7%) | 10.1 | 35.2 | 27.6 | 0.35 | 349.4 | 616 | 3725 |
| (8.6 – 11.5) | (32.2 – 38.1) | (23.3 – 32.0) | (0.28 – 0.42) | (310.4 – 388.4) | (241 – 992) | (3065 – 4386) | ||
| p value | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Abbreviations: CI, confidence interval; EQ-5D, EuroQol-5 Dimension; MMSE, Mini-Mental State Examination; NPI12, Neuropsychiatric Inventory-12; ZBI, Zarit Burden Interview;
*
Based on small sample size.