Table II.

Effect of Cocaine use and HIV infection on CES-D and Neurocognitive Scores

	CES-D (actual score; n=288)			Neurocognitive Summary (NPZ16; n=242)
Fixed Effects	Estimate	SE	p-value	Estimate	SE	p-value
Baseline age	−0.2754	0.1052	0.009	−0.00250	0.006183	0.687
Education < 12 years	2.4459	1.1058	0.028	0.1064	0.08034	0.187
Cocaine Use	0.4314	2.0732	0.018	−0.2806	0.1435	0.069
HIV Infection	−0.6870	1.2460	0.105	0.08344	0.08905	0.039
Smoker	1.5933	1.1502	0.167	0.002895	0.08344	0.972
Cocaine * HIV Infection	5.7119	2.6552	0.032	0.2151	0.1836	0.243
Years in Study	−0.1792	0.1730	0.004	0.04574	0.01262	<0.001
HIV Infection* Years in Study	0.1884	0.2296	0.134	−0.03825	0.01655	0.020
Cocaine * Years in Study	0.01700	0.3755	0.028	0.01033	0.02730	0.570
Cocaine * HIV Infection * Years in Study	−1.1010	0.4823	0.023	−0.00163	0.03340	0.961

Negative years in study estimates indicate a steeper slope of cognitive decline.

Abbreviations: CES-D, Center for Epidemiological Studies Depression Scale; SE, standard error; *, interaction term