Table III.

Predictors of Depressive Trajectories in Latent Class Mixed Effects Models.

CES-D	All participants (n=160)		HIV+ participants (n=86)
	Unadjusted OR (95%Cl), p-value	Adjusted OR (95%Cl), p-value	Unadjusted OR (95%Cl), p-value	Adjusted OR (95%Cl), p-value
Baseline Age	0.96 (0.89–1.03), 0.30		0.89 (0.79–1.00), 0.05
Educationa	2.75 (1.43–5.28), <0.01	2.50 (1.26–4.97), <0.01	2.32 (0.99–5.40), 0.05
Cocaine useb	3.71 (1.75–7.88), <0.001	3.04 (1.38–6.69), <0.01	5.92 (2.17–16.14), <0.001	8.41 (2.73–25.83), <0.001
Heavy Drinking	2.40 (1.20–4.79), 0.01	2.19 (1.04–4.59), 0.04	2.56 (1.03–6.36), 0.04
HIV Infection	1.16 (0.61–2.21), 0.64
Viral Load ≥ 400c			1.79 (0.77–4.17), 0.17	3.07 (1.10–8.56), 0.03
CD4 count < 350d			1.06 (0.45–2.51), 0.88

Unadjusted and adjusted odds ratio (OR) for predictors of membership in the latent class representing persistent high depressive symptoms versus low/moderate symptoms

^a- OR for ≤12 years of education

^b- Daily/weekly use reported at first 2 visits in study interval

^c- Baseline viral load (plasma HIV RNA, copies/mL)

^d- Baseline CD4 count (cells/mm³)