Table 3. Predicting the psychosis-spectrum.
Outcomes |
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---|---|---|---|---|---|---|---|---|---|---|---|---|
Predictors |
Emergence or persistence of psychosis |
Change in total SOPS score |
Change in factor 1: Unusual thoughts and experiences |
Change in factor 2: Impairment in social, occupational and daily functioning |
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Coeff. | z | P | Coeff. | t | P | Coeff. | t | P | Coeff. | t | P | |
T1 age | 0.15 | 1.76 | 0.08 | 0.02 | 1.25 | 0.22 | 0.01 | 0.31 | 0.76 | 0.03 | 1.53 | 0.13 |
Sex | 2.12 | 1.99 | 0.05 | 0.25 | 1.35 | 0.18 | 0.59 | 2.92 | 0.01 | 0.01 | 0.04 | 0.97 |
T1 factor 1 | 1.55 | 2.38 | 0.02 | −0.18 | −1.54 | 0.13 | −0.78 | −6.18 | 0.00 | 0.00 | 0.03 | 0.98 |
T1 factor 2 | −0.17 | −0.23 | 0.82 | −0.42 | −2.65 | 0.01 | −0.23 | −1.38 | 0.18 | −0.50 | −2.75 | 0.01 |
T1 GAF | −0.04 | −1.00 | 0.32 | 0.01 | 1.25 | 0.22 | 0.00 | −0.34 | 0.73 | 0.01 | 1.19 | 0.24 |
T1 mood disorder | 1.31 | 1.06 | 0.29 | 0.70 | 2.55 | 0.01 | 1.12 | 3.79 | 0.00 | 0.50 | 1.61 | 0.11 |
T1 anxiety disorder | 1.82 | 1.96 | 0.05 | 0.21 | 0.99 | 0.33 | 0.22 | 0.98 | 0.33 | 0.20 | 0.83 | 0.41 |
T1 ADHD | −0.81 | −0.90 | 0.37 | 0.18 | 0.85 | 0.40 | −0.02 | −0.08 | 0.93 | 0.31 | 1.33 | 0.19 |
Lifetime psychotropic use | 0.94 | 1.03 | 0.30 | −0.03 | −0.14 | 0.89 | −0.03 | −0.14 | 0.89 | 0.07 | 0.29 | 0.77 |
T1 global cognition | −2.50 | −2.34 | 0.02 | −0.59 | −3.37 | 0.00 | −0.39 | −2.18 | 0.03 | −0.57 | −2.98 | 0.00 |
Change in global cognition | −1.21 | −1.12 | 0.26 | −0.81 | −3.79 | 0.00 | −0.52 | −2.37 | 0.02 | −0.83 | −3.56 | 0.00 |
CNB trials | −1.74 | −1.93 | 0.05 | 0.02 | 0.12 | 0.91 | 0.07 | 0.39 | 0.70 | 0.16 | 0.91 | 0.37 |
Abbreviations: ADHD, attention-deficit hyperactivity disorder; CNB, Computerized Neurocognitive Battery; Coeff, coefficient; GAF, global assessment of function; SOPS, Scale of Prodromal Symptoms; T1, time 1/initial evaluation.
CNB trials was added as covariate because of possible practice effects and non-uniform total number of trials administered to participants who are evaluated at 2–4 time points. Bolded entries highlight statistical significance.