Table 1.

The sequences of the wild-type (WT) and mutated LPK ChREs

Oligonucleotide	Sequence
WT	5′-GGGCGCACGGGGCACTCCCGTGGTTCC-3′
	3′-CCCGCGTGCCCCGTGAGGGCACCAAGG-5′
M1	5′-GGGCGaACGGGGCACTCCCGTtGTTCC-3′
	3′-CCCGCtTGCCCCGTGAGGGCAaCAAGG-5′
M2	5′-GGGCGCcCGGGGCACTCCCGgGGTTCC-3′
	3′-CCCGCGgGCCCCGTGAGGGCcCCAAGG-5′
M3	5′-GGGCGCAaGGGGCACTCCCtTGGTTCC-3′
	3′-CCCGCGTtCCCCGTGAGGGaACCAAGG-5′
M4	5′-GGGCGCACtGGGCACTCCaGTGGTTCC-3′
	3′-CCCGCGTGaCCCGTGAGGtCACCAAGG-5′
M5	5′-GGGCGCACGtGGCACTCaCGTGGTTCC-3′
	3′-CCCGCGTGCaCCGTGAGtGCACCAAGG-5′
M6	5′-GGGCGCACGGtGCACTaCCGTGGTTCC-3′
	3′-CCCGCGTGCCaCGTGAtGGCACCAAGG-5′
M3/5	5′-GGGCGCAtGcGGCACTCgCaTGGTTCC-3′
	3′-CCCGCGTaCgCCGTGAGcGtACCAAGG-5′
S−1	5′-GGGCGCACGGGGCCTCCCGTGGTTCCT-3′
	3′-CCCGCGTGCCCCGGAGGGCACCAAGGA-5′
S+1	5′-GGGCGCACGGGGCACTTCCCGTGGTTCC-3′
	3′-CCCGCGTGCCCCGTGAAGGGCACCAAGG-5′

The E-boxes are in boldface type. Mutations within the E-box are indicated by lowercase letters. S−1 and S+1 indicate the deletion or addition, respectively, of one base between the two E-boxes.