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. Author manuscript; available in PMC: 2018 Jun 8.
Published in final edited form as: N Engl J Med. 2017 May 21;376(23):2235–2244. doi: 10.1056/NEJMoa1703058

Figure 1. Cumulative Probability of Completion of the 3-Hour Bundle, Administration of Broad-Spectrum Antibiotics, and Completion of the Initial Intravenous-Fluid Bolus after the Time That the Sepsis Protocol Was Initiated.

Figure 1

The 3-hour bundle for the care of patients with sepsis or septic shock had to include receipt of the following care within 3 hours: obtaining of a blood culture before the administration of antibiotics, measurement of the serum lactate level, and the administration of broad-spectrum antibiotics; however, protocols could be tailored by each hospital. We also assessed the time to the administration of broad-spectrum antibiotics and the time to the completion of an initial bolus of intravenous fluids.