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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Transl Cancer Res. 2017 Jun;6(3):620–632. doi: 10.21037/tcr.2017.05.19

Figure 2.

Figure 2

Morphology and immunohistochemistry of ccpRCC. (A) On histology, ccpRCC exhibits a papillary architecture under low magnification (HE, ×40); (B) under higher magnification, the tumor shows cells with clear cytoplasm with luminally oriented low grade nuclei, away from the basement membrane (HE, ×200); (C) by immunohistochemistry, ccpRCC shows strong membranous staining for CK7 (×200); (D) strong “cup shaped” staining for CA-IX with characteristic absence of staining along the lumen (×200). ccpRCC, clear cell papillary renal cell carcinoma; CA-IX, carbonic anhydrase IX.