Table 3.

Arterial blood variables at baseline and near exercise termination for control constant load exercise trial

	Baseline		Termination		Change from baseline
	M	W	M	W	M	W
[K+] (mmol l−1)	4.0 ± 0.2	3.8 ± 0.1	5.5 ± 0.1†	5.4 ± 0.1†	1.4 ± 0.3	1.6 ± 0.1
[Ca2+] (mmol l−1)	1.19 ± 0.01	1.17±.01	1.25 ± 0.02†	1.26 ± 0.01†	0.05 ± 0.03	0.09 ± 0.02
[Na+] (mmol l−1)	142 ± 0.1	142 ± 5	145 ± 0.9†	146 ± 0.9†	3.1 ± 0.9	3.8 ± 0.8
[Cl−] (mmol l−1)	108 ± 1	110 ± 1	112 ± 0.9†	112 ± 0.9†	3.6 ± 1.0	2.3 ± 0.5
[Hb] (g dl−1)	14.5 ± 0.3	12.9 ± 0.2*	15.6 ± 0.3†	14.1 ± 0.2†, *	1.2 ± 0.3	1.1 ± 0.2
Hct (%)	44 ± 1	40 ± 1*	48 ± 1†	43 ± 1†, *	3.5 ± 0.8	3.4 ± 0.5
FHHb (%)	1.3 ± 0.2	1.5 ± 0.2	4.4 ± 0.6†	4.2 ± 0.6†	3.1 ± 0.7	2.7 ± 0.7
[HCO3 −] (mmol l−1)	22.4 ± 0.3	20.3 ± 0.5*	12.1 ± 0.9†	10.6 ± 0.9†, *	−10.2 ± 1.0	−9.6 ± 1.4
Base excess (mmol l−1)	−1.4 ± 0.4	−3.2 ± 0.3*	−14.6 ± 1.2†	−16.9 ± 1.3†	−13.2 ± 1.2	−13.7 ± 1.2
$P_{\mathrm{a}{\mathrm{O}}_2}$ (mmHg)	99 ± 4	100 ± 1	94 ± 3	96 ± 2	−5 ± 5	−3 ± 3
(range)	(89–117)	(93–104)	(81–111)	(86–106)	(−23–21)	(−17–8)
$P_{\mathrm{aC}{\mathrm{O}}_2}$ (mmHg)	37 ± 1	34 ± 2	31 ± 1†	31 ± 1†	− ± 2	−3 ± 1
(range)	(29–41)	(26–38)	(24–34)	(28–33)	(−17–0)	(−6–2)
$P_{\mathrm{A}{\mathrm{O}}_2}$ (mmHg)	110 ± 3	110 ± 2	117 ± 3†	117 ± 1†	7 ± 3	7 ± 1
(range)	(100–124)	(106–120)	(113–123)	(113–120)	(−5–22)	(0–10)
A‐a$D_{{\mathrm{O}}_2}$ (mmHg)	11 ± 1	9 ± 2	23 ± 3†	21 ± 3†	12 ± 3	11 ± 3
(range)	(5–15)	(7–17)	(12–33)	(8–34)	(1–23)	(−1–25)
$C_{\mathrm{a}{\mathrm{O}}_2}$ (ml dl−1)	20.1 ± 0.5	18.1 ± 0.2*	21.0 ± 0.3†	18.9 ± 0.4†, *	0.9 ± 0.4	0.7 ± 0.2
1 $C_{\mathrm{a}{\mathrm{O}}_2}$ (ml dl−1)	20.1 ± 0.5	18.1 ± 0.2*	21.7 ± 0.4†	19.6 ± 0.4†, *	1.6 ± 0.4	1.4 ± 0.2

Values are means ± SEM. M, men; W, women; A‐a$D_{{\mathrm{O}}_2}$, alveolar‐to‐arterial oxygen gradient; $C_{\mathrm{a}{\mathrm{O}}_2}$, arterial oxygen content; ¹ $C_{\mathrm{a}{\mathrm{O}}_2}$, ideal $C_{\mathrm{a}{\mathrm{O}}_2}$ if no desaturation was present; FHHb, fraction of deoxyhaemoglobin; Hb, haemoglobin; Hct, haematocrit; $P_{\mathrm{aC}{\mathrm{O}}_2}$, arterial oxygen tension; $P_{\mathrm{A}{\mathrm{O}}_2}$, alveolar oxygen tension. ^*Significantly different from men; †significantly different from baseline; P < 0.05.