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Stability of Cyp7a1 and TFR1 mRNA. A: TFR1 mRNA was measured at the times indicated. TFR1 mRNA became stable after DFO treatment, the half-life of TFR1 decreased after iron-dextran treatment. B: Cyp7a1 mRNA was measured at the times indicated. Cyp7a1 mRNA became stable after DFO treatment, while the half-life of Cyp7a1 decreased four times in comparison with untreated controls after iron-dextran treatment. GAPDH was used as a control gene.
