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. 2017 Jun 20;58(8):1692–1701. doi: 10.1194/jlr.M077479

TABLE 1.

Hepatic lipid content in LD-fed mice of the indicated genotype

Genotype TC FC CE PL FFA BA
WT (6) 159.8 ± 22.9 27.5 ± 1.3 132.3 ± 22.9 85.6 ± 2.4 86.6 ± 5.6a 21.8 ± 9.1a
Cd36−/− (6) 159.8 ± 10.4 31.0 ± 4.8 128.8 ± 10.9 92.5 ± 5.0 85.0 ± 4.9a 27.1 ± 15.1a
L-Fabp−/− (5) 147.5 ± 11.6 24.0 ± 3.7 123.6 ± 12.3 95.8 ± 4.6 80.7 ± 9.1a 19.6 ± 4.1a
DKO (6) 159.4 ± 24.9 32.4 ± 1.9 127.0 ± 26.7 93.9 ± 2.7 132.9 ± 10.9b 33.2 ± 11.2a

Mice from four experimental groups (n per group) were fed a LD for 4 weeks. Hepatic lipids were extracted and analyzed (Materials and Methods). Hepatic lipid content is expressed as mean ± SE (µg/mg protein), except FFA (nmol/mg protein). The difference between values associated with different superscript letters for the parameters indicated in each vertical column is statistically significant (P < 0.05). BA, bile acid; CE, cholesteryl ester; FC, free cholesterol; FFA, free fatty acid; PL, phospholipid; TC, total cholesterol.