Table 1.

Incubation periods in Tg(MoPrP)4053 mice following permanent implantation of wires contaminated with RML prions for different durations

Contaminating procedure	Time	Incubation period (days)a	n/n0b
Transient insertion of wire in terminal RML-infected brain	30 sec	78 ± 2	5/5
	90 sec	83 ± 1	4/4
	5 min	84 ± 4	4/4
Incubating wire in 10% RML brain homogenate	15 min	88 ± 3	3/3
	1 h	89 ± 2	4/4
	4 h	86 ± 4	4/4
	16 h	82 ± 4	4/4

^aData reported as mean ± standard error of the mean.

^bn, number of mice showing clinical signs of disease; n₀, number of mice inoculated.