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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: J Allergy Clin Immunol. 2016 Oct 11;139(6):1873–1884.e10. doi: 10.1016/j.jaci.2016.09.018

Fig 4. KLF4 is repressed by Notch signaling.

Fig 4

A, Sections of healthy human skin (top) and cytospun in vitro–generated p-LCs, moLCs, and moDCs (bottom). B, TGF-β1–dependent upregulation/downregulation of Notch target genes after 6 and 24 hours (n = 3). C, NOTCH1 and JAG2 surface expression of CD34+ progenitors and p-LC generation cultures (n = 4). D, FACS analysis of intracellular active NOTCH1 (aN1) of day 5 moLCs and moDCs and day 7 p-LCs (n = 4).