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. 2017 Aug 1;14(8):e1002367. doi: 10.1371/journal.pmed.1002367

Table 2. Overall risk for GDM in second pregnancy by interpregnancy change in BMI (n = 24,198), The Medical Birth Registry of Norway 2006–2014.

Interpregnancy BMI Change
(kg/m2)
RR for GDM in
Second Pregnancy
Total GDM /1000 Crude
RR
95% CI aRR* 95% CI
<−2 15/1,692 8.9 0.8 0.5–1.4 0.9 0.5–1.6
−2 til <−1 34/2,384 14.3 1.3 0.9–1.9 1.3 0.9–2.0
−1 til <1 126/11,512 10.9 1.0 Reference 1.0 Reference
1 til <2 79/3,814 20.7 1.9 1.4–2.5 2.0 1.5–2.7
2 til <4 97/3,279 29.6 2.7 2.1–3.5 2.6 2.0–3.5
≥4 88/1,517 58.0 5.3 4.1–6.9 5.4 4.0–7.4
Total 439/24,198 18.1 24,198 20,824

a, adjusted; BMI, Body Mass Index; GDM, Gestational Diabetes Mellitus; RR, relative risk.

*Analysis adjusted for maternal age during the second pregnancy (<25 (reference), 25–29, 30–34, ≥35 years), maternal country of birth (Nordic [reference]/non-Nordic), maternal education (<11, 11–13, ≥14 [reference] years), smoking in pregnancy (no[reference],/yes), interpregnancy interval (<12, 12–23 [reference], 24–35, ≥36 months), and year of the second birth (continuous).