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. 2017 Aug 1;12(8):e0182089. doi: 10.1371/journal.pone.0182089

Fig 1. Clinical and tissue phenotypes in the SMZ/TMP-treated WT and Cxcr2-/- mice.

Fig 1

(A) Development of jaundice and (B) survivability were examined following RRV-injection (N = 28–110 per group). Black bar: comparison between regular-WT and SMZ/TMP-WT; yellow bar: regular-WT and regular-Cxcr2-/-; green bar, regular-WT and SMZ/TMP- Cxcr2-/-; gray bar, SMZ/TMP-WT and regular-Cxcr2-/-; blue bar, SMZ/TMP-WT and SMZ/TMP-Cxcr2-/-. *, P<0.05; **, P<0.01; ***, P<0.001; ****, P<0.0001. (C) Longitudinal sections of EHBDs and liver sections stained with H&E from the SMZ/TMP-treated Cxcr2-/- mice. Unobstructed lumen and improved portal inflammation are observed in those Cxcr2-/- mice alive at 14 days after RRV-injection (N = 4–5 per group); magnified with x20 (bar = 50μm).