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. 2017 Aug 1;12(8):e0181823. doi: 10.1371/journal.pone.0181823

Fig 7. DHB disrupts interactions between hERG and chaperones.

Fig 7

(A) Western blot analysis of Hsp70 and Hsp90 after 24 h incubation with 1 μM and 10 μM DHB. Hsp90 expression was concentration-dependently reduced while Hsp70 expression did not change. *P < 0.05 vs. control, n = 4. (B) Immunoprecipitation results show increased and decreased interaction between hERG and Hsp70 or Hsp90 respectively after treatment with 10 μM DHB. *P < 0.05 vs. control, n = 3.