Table 1.
Association of KIAA1522 levels with clinicopathological features of 342 patients with ESCC
| Clinicopathological features | KIAA1522 expression
|
Total | P-value | |
|---|---|---|---|---|
| Negative (%) | Positive (%) | |||
| All patients | 185 (54) | 157 (46) | 342 | |
| Age (years) | 0.632 | |||
| <60 | 92 (55.4) | 74 (44.6) | 166 | |
| ≥60 | 93 (52.8) | 83 (47.2) | 176 | |
| Gender | 0.837 | |||
| Male | 135 (55.4) | 113 (44.6) | 248 | |
| Female | 50 (53.2) | 44 (46.8) | 94 | |
| TNM classification | ||||
| pT | 0.625* | |||
| T1 | 8 (66.7) | 4 (33.3) | 12 | |
| T2 | 105 (51.5) | 99 (48.5) | 204 | |
| T3 | 40 (56.3) | 31 (43.7) | 71 | |
| T4 | 32 (58.2) | 23 (41.8) | 55 | |
| pN | 0.361 | |||
| N0 | 37 (49.3) | 38 (50.7) | 75 | |
| N1 | 147 (55.5) | 118 (44.5) | 265 | |
| Histology grade | 0.030 | |||
| Good (G1) | 42 (66.7) | 45 (33.3) | 87 | |
| Moderate (G2) | 106 (51.5) | 96 (48.5) | 202 | |
| Poor (G3) | 36 (56.3) | 15 (43.7) | 51 | |
| AJCC6 stage | 0.921 | |||
| I | 14 (56.0) | 11 (44.0) | 25 | |
| II | 101 (53.2) | 89 (46.8) | 190 | |
| III | 69 (55.2) | 56 (44.8) | 125 | |
Note:
*
Fisher’s exact test.
Abbreviations: ESCC, esophageal squamous cell carcinoma; TNM, tumor, regional lymph node, distant metastasis; pT, pathologic T stage; pN, lymph node metastases; AJCC6, American Joint Committee on Cancer (Sixth Edition).