Table 2. Characteristics of the fMRI sample.
CTR (n = 15) | PD-CN (n = 69) | PD-MCI (n = 15) | CTR vs PD-CN (p value) | CTR vs PD-MCI (p value) | PD-CN vs PD-MCI (p value) | |
---|---|---|---|---|---|---|
Age (y) | 66.4(9.1) | 61.0(10.4) | 63.5(8.2) | 0.066 | 0.372 | 0.378 |
Sex (M/F) | 13/2 | 46/23 | 11/4 | 0.125 | 0.361 | 0.616 |
Education (y) | 16.5(2.3) | 15.3(2.9) | 14.2(3.1) | 0.112 | 0.024 | 0.204 |
UPDRS-III | - | 18.2(9.1) | 21.8(8.9) | - | - | 0.161 |
HY stage | - | 1.7(0.5) | 1.8(0.4) | - | - | 0.297 |
MoCA | 27.9(1.6) | 27.6(1.9) | 24.0(3.7) | 0.615 | 0.001 | <0.001 |
Disease duration (y) | - | 1.2(0.9) | 2.4(1.5) | - | - | <0.001 |
Means are followed by standard deviations. Differences in age, years of education, and MoCA scores were assessed using Student’s T test. Differences in gender were assessed using a χ2 test. CTR, controls; PD-CN, Parkinson’s disease cognitively normal; PD-MCI, Parkinson’s disease with mild cognitive impairment; UPDRS-III, Unified Parkinson’s disease rating scale–Part III; HY stage, Hoehn and Yahr stage; MoCA, Montreal cognitive assessment scale.