Table 3.

Association between interpretive agreement and patient and case characteristics for all cases, and for Atypia cases (phase I diagnosis) only.

Case Characteristics	All Phase I interpretations			Interpreted as Atypia in Phase I a
	All Cases	Agreement with Phase I Interpretation		Atypia Cases a	Agreement with Phase I Interpretation
	N (%)	Rate (95% CI)	p-value	N (%)	Rate (95% CI)	p-value
Total	240 (100.0)	0.79 (0.77 - 0.81)	--	50 (100)	0.53 (0.47 - 0.59)	--
Patient Age (yrs) b
40-49	118 (49.2)	0.79 (0.76 - 0.81)	0.34	25 (50.0)	0.52 (0.45 - 0.59)	0.31
50-59	67 (27.9)	0.78 (0.74 - 0.81)		15 (30.0)	0.50 (0.42 - 0.58)
60-69	29 (12.1)	0.82 (0.78 - 0.86)		5 (10.0)	0.62 (0.51 - 0.72)
70+	26 (10.8)	0.78 (0.73 - 0.82)		5 (10.0)	0.57 (0.45 - 0.67)
Breast Densityc
Low Density	118 (49.2)	0.81 (0.78 - 0.83)	0.007	21 (42.0)	0.51 (0.45 - 0.58)	0.36
High Density	122 (50.8)	0.77 (0.75 - 0.79)		29 (58.0)	0.55 (0.48 - 0.62)
Biopsy Type
Core needle biopsy	138 (57.5)	0.78 (0.76 - 0.81)	0.70	31 (62.0)	0.56 (0.50 - 0.62)	0.037
Excisional biopsy	102 (42.5)	0.79 (0.77 - 0.81)		19 (38.0)	0.48 (0.41 - 0.56)
Average Number of Diagnoses per Cased
1	14 (5.8)	0.98 (0.95 - 0.99)	<0.001	0 (0.0)	(-)	0.49
>1 and ≤2	194 (80.8)	0.79 (0.77 - 0.81)		39 (78.0)	0.53 (0.47 - 0.59)
>2 and ≤3	30 (12.5)	0.73 (0.68 - 0.77)		10 (20.0)	0.56 (0.45 - 0.65)
>3	2 (0.8)	0.42 (0.24 - 0.61)		1 (2.0)	0.33 (0.10 - 0.68)

^aIncludes all interpretations considered to be Atypia by pathologists in Phase I.

^bThe patient's age and type of biopsy information were provided to participants.

^cLow density (almost entirely fat or scattered fibroglandular densities) and high density (heterogeneously or extremely dense). Breast density information was not provided to participants.

^dRepresents the number of diagnostic subtypes checked by pathologists in phase I per each interpretation, averaged at the level of the case.