Table 2. Evaluation of TP-EIA and TRUST in comparison with the TPPA assay.
| Assay and result | TPPA | % Positive percent agreement (95%CI) | % Negative percent agreement (95%CI) | % total percent agreement (95%CI) | Kappa value (95%CI) | |
|---|---|---|---|---|---|---|
| Positive | Negative | |||||
| TP-EIA | ||||||
| Positive | 213 | 14 | 100 | 97.9 | 98.4 | 0.960 |
| Negative | 0 | 638 | (100–100) | (96.7–99.0) | (97.5–99.2) | (0.937–0.979) |
| TRUST | ||||||
| Positive | 123 | 38 | 57.7 | 94.2 | 85.2 | 0.566 |
| Negative | 90 | 614 | (51.1–64.4) | (92.4–96.0) | (82.8–87.6) | (0.493–0.627) |
Abbreviations: TRUST, toluidine red unheated serum test; TPPA, Treponema pallidum particle agglutination; TP-EIA, Treponema pallidum enzyme immunoassay.