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. 2017 Jul 20;11(7):e0005758. doi: 10.1371/journal.pntd.0005758

Table 3. Evaluation of traditional algorithm and ECDC algorithm in comparison with reverse algorithm.

Assay and result Reverse algorithm % Positive percent agreement (95%CI) % Negative percent agreement (95%CI) % total percent agreement (95%CI) Kappa value (95%CI)
Positive Negative
Traditional algorithm
 Positive 123 0 57.2 100 89.4 0.668
 Negative 92 650 (50.5–63.9) (100–100) (87.3–91.4) (0.603–0.729)
ECDC algorithm
 Positive 213 0 99.1 100 99.8 0.994
 Negative 2 650 (97.8–100) (100–100) (99.4–100) (0.984–1.0)

Abbreviations: ECDC, European Centre for Disease Prevention and Control.