Figure 2. Negative stain EM structure of ^RERdj3^WT reveals the native tetramer.

1. 2D reference‐free class averages of negative stained ^RERdj3^WT complexes show a diamond‐like shape.
2. A 19 Å resolution structure of the ^RERdj3 tetramer is shown in 4 orthogonal views, displaying the flat, diamond‐shaped organization of the tetramer. The EM map is deposited in the EM data bank (EMD‐8707).
3. A crystal structure of the ERdj3 homolog DNAJB1 (PDB: 2QLD; Hu et al, 2008) is docked into the ^RERdj3 EM density to depict the domain organization.