Figure 6. Beta-endorphin secreted by AMPA application was inhibited by Cp-AMPAR blocker, IEM 1460 under fed but not under fasted conditions.
(a) Under fed condition, beta-endorphin secretion from hypothalamus slice was significantly increased by AMPA application compared to aCSF and AMPA + IEM 1460. (b) Under fasted condition, beta-endorphin secretion was not increased by AMPA, aCSF and AMPA + IEM 1460 treatment. Results are expressed mean ± SEM. * indicates p<0.05, two-way analysis of variance (ANOVA) and Tukey multiple comparison posthoc test.