Fig. 7.

Effect of PT-GS-KO on Rhcg and Rhbg expression on dietary protein restriction. Top, Rhcg immunolabel in PT-GS-KO mice fed 20% or 6% protein diet. In PT-GS-KO mice, dietary protein restriction decreased Rhcg expression in inner stripe of the outer medulla intercalated cells (arrows) and principal cells (unlabeled). Bottom, Rhbg immunolabel in PT-GS-KO mice fed 20% or 6% protein diet. There was no observable difference in Rhbg expression in the inner stripe of the outer medulla intercalated cells in response to dietary protein restriction in PT-GS-KO mice.