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Acute dose response to norepinephrine (NE) in anesthetized control and MatSep rats. A: MatSep did not affect NE-induced increases in mean arterial pressure (MAP). B: no dose-dependent changes in HR were found between groups. C: renal blood flow (RBF) response was significantly attenuated in MatSep rats. D: calculated renal vascular resistance (RVR) was reduced in MatSep rats. n = 4 Control and 5 MatSep. P < 0.05 vs. baseline (¶), previous dose (#), and control same dose (*).
