Table 3. Estimated regression coefficients examining the association of obesity, LMM and obesity with LMM with cardiovascular risk.
| Non-obese non-LMM§ | Non-obese with LMM | Obese without LMM | Obese with LMM | |||||
|---|---|---|---|---|---|---|---|---|
|
|
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| Intercept | P | Coeff. | P | Coeff. | P | Coeff. | P | |
|
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| Model 1a | ||||||||
|
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| MetS (z score) | -0.089 | <.001 | 0.344 | <.001 | 0.524 | <.001 | 0.771 | <.001 |
| WC (cm) | 76.68 | <.001 | 10.45 | <.001 | 16.49 | <.001 | 24.15 | <.001 |
| SBP (mm Hg) | 113.45 | <.001 | 3.72 | <.001 | 4.22 | .16 | 11.24 | <.001 |
| DBP (mm Hg) | 69.92 | <.001 | 1.69 | .04 | 3.93 | .06 | 4.81 | <.001 |
| TG (mg/dL) | 79.38 | <.001 | 14.36 | .01 | 17.48 | .24 | 50.59 | <.001 |
| HDL (m/dL) | 39.19 | <.001 | -2.66 | .04 | -5.71 | .08 | -6.38 | <.001 |
| TC/HDL | 3.97 | <.001 | 0.46 | .002 | 0.62 | .11 | 1.07 | <.001 |
| HOMA-IR | 1.48 | <.001 | 0.41 | .004 | 0.70 | .06 | 1.77 | <.001 |
|
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| Model 2b | ||||||||
|
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| MetS (z score) | -0.109 | <.001 | 0.32 | <.001 | 0.46 | .001 | 0.72 | <.001 |
| WC (cm) | 75.68 | <.001 | 9.32 | <.001 | 12.82 | <.001 | 21.11 | <.001 |
| SBP (mm Hg) | 113.39 | <.001 | 3.44 | <.001 | 3.22 | .29 | 10.33 | <.001 |
| DBP (mm Hg) | 69.87 | <.001 | 1.50 | .13 | 3.30 | 0.07 | 4.24 | <.001 |
| TG (mg/dL) | 78.84 | <.001 | 14.57 | .013 | 18.46 | .23 | 51.59 | <.001 |
| HDL (m/dL) | 40.28 | <.001 | -2.23 | .08 | -4.64 | .16 | -5.78 | <.001 |
| TC/HDL | 3.83 | <.001 | 0.41 | .007 | 0.47 | .23 | 0.99 | <.001 |
| HOMA-IR | 1.42 | <.001 | 0.37 | .01 | 0.58 | .13 | 1.69 | <.001 |
Obesity: BMI z > 2 SD for age and sex. Sarcopenia: Total Lean Mass (TLM) ≤ 66.1% in males and ≤ 56.3% in females.
a
Model 1 adjusted for sex (female=1).
b
Model 2 adjusted for sex, early onset obesity (≤5y), and short maternal breast feeding (≤3 mo).
§
Non-obese non-sarcopenic participants are the reference group. Coefficients are the mean difference between a given category and the reference group.