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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Exp Neurol. 2017 Apr 1;293:159–171. doi: 10.1016/j.expneurol.2017.03.026

Table 1.

Comparison of seizure characteristics due to the PFE and A/PFE paradigms.

Average temperature
at 1st seizure (°C)		 Average
latency to 1st
seizure (s)		 Average
severity		 Total
number of
seizures
PFE 41.1 ± 0.2 802 ± 58.0 2.6 ± 0.2 1.3 ± 0.2
A/PFE 40.8 ± 0.2 765 ± 44.7 2.9 ± 0.2 2.9 ± 0.7*

The average temperature of the first FS, average latency of the first FS, average seizure severity, and average total number of seizures experienced during each paradigm are shown. Average temperature, latency and total number of seizures were analyzed with the Student T-test. The Mann-Whitney test was used for seizure severity. A statistically significant difference was identified in the total number of seizures observed in the mice that were subjected to the PFE paradigm compared to the A/PFE paradigm.

*

p<0.05.

Values are shown as mean ± SEM. 12 mice for each genotype and treatment were evaluated per paradigm.