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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Exp Neurol. 2017 Apr 1;293:159–171. doi: 10.1016/j.expneurol.2017.03.026

Table 2.

The A/PFE paradigm leads to increased seizure severity in adult RH/+ mice.

Controls A/PFE
WT (n= 8) RH/+ (n= 9) WT (n= 9) RH/+ (n= 11)
% Exhibiting Seizures 0% (0/8) 11% (1/9) 11% (1/9) 45% (5/11)
Average severity N/A 1.5 ± 0.5 0.5 ± 0.2 2.8 ± 0.4*

Values represent the percentage of mice exhibiting spontaneous seizures and the corresponding average seizure severity. Statistical analysis of the percentage of mice exhibiting seizures was determined with the Fisher exact test and seizure severity was compared with the Kruskal-Wallis test. A statistically significant difference was observed in the severity of the seizures in RH/+ mice that were subjected to the A/PFE paradigm.

*

p<0.05.

Values are shown as mean ± SEM.