Table 3.

Intrinsic firing properties of CA3 pyramidal neurons.

	Control		A/PFE
	WT (n= 8)	RH/+ (n= 6)	WT (n= 8)	RH/+ (n= 5)
AP Threshold (mV)	− 43 ± 1.6	−44 ± 2.2	−52 ± 2.2 *	−52 ± 2.2 *
AP Peak (mV)	87 ± 2.1	71 ± 2.5 **	86 ± 3.5	73 ± 5.5
AP Half-width (ms)	2 ± 0.1	2 ± 0.3	2 ± 0.2	2 ± 0.2
AP Max. rise slope (mV/ms)	144 ± 13.1	109 ± 14	137 ± 17.7	128 ± 24
AP AHP (mV)	−39 ± 1.7	−38 ± 6.5	−50 ± 7.3	−44 ± 3.6

AP threshold, peak, half-width, maximum rise slope, and AFP (after hyperpolarization) are shown as mean ± SEM;

^*p<0.05 compared to control WT;

^**p<0.05 compared to control WT and WT APFE; 1-way ANOVA followed by Holm-Sidak’s test for multiple comparisons. n= number of cells.