Table 2. Risk of oral feeding on anastomotic leakage after esophagectomy.

Study	Design	N (I/C)	% esophagectomy	Anastomosis	OR (95% CI)	P value
Early oral feeding
Lassen et al.	Prospective	447 (220/227)	2	Mixed	0.67 (0.30–1.53)	0.345
Mahmoozadeh et al.	Prospective	109 (54/55)	75	Mixed	1.02 (0.14–7.51)	0.985
Sun et al.	Prospective	133 (68/65)	100	Cervical	0.47 (0.04–5.31)	0.542
Weijs et al.	Prospective	100 (50/50)	100	Thoracic	0.52 (0.18–1.44)	0.207
Prolonged enteral feeding
Tomaszek et al.	Retrospective	386 (110/276)	100	Mixed	4.84 (1.45–16.14)	0.010*
Bolton et al.	Retrospective	120 (33/87)	100	Cervical	9.57 (1.20–76.7)	0.034*

N, number of patients; I, number of patients in intervention group; C, number of patients in control group. *, P<0.05.