Table 3.
Adjusted odds ratio of clinical events within 180 days after pre versus postoperative start of LMWH
| Clinical events | Total (%) | Preoperative LMWH (%) |
Postoperative LMWH (%) |
Adjusted OR | CI | p value |
|---|---|---|---|---|---|---|
| Bleeding events: | ||||||
| D64 + R57 + R58 + K92 + NFW | 686 (2.7) | 279 (2.8) | 407 (2.7) | 1.04 | 0.88–1.22 | 0.660 |
| Reoperation for bleeding/infection: | ||||||
| NFW | 407 (1.6) | 159 (1.6) | 248 (1.6) | 1.09 | 0.88–1.34 | 0.425 |
| Thromboembolic episodes: | ||||||
| I26 + I80 + I82 + I87 + I74 | 411 (1.6) | 165 (1.7) | 246 (1.6) | 1.03 | 0.84–1.27 | 0.786 |
| Other complications: | ||||||
| I20 + I21 + I23 + I24 + I64 + G45 + G46 + L02 + I49 + D65 + J80 | 981 (3.9) | 456 (4.6) | 525 (3.5) | 0.86 | 0.76–0.99 | <0.034 |
| Myocardial ischemia: | ||||||
| I20 + I21 + I23 + I24 | 731 (3.1) | 370 (3.7) | 401 (2.6) | 0.83 | 0.76–0.99 | <0.017 |
| Mortality | ||||||
| 30 days | 54 (0.21) | 30 (0.3) | 24 (0.2) | 0.53 | 0.30–0.94 | <0.030 |
| 90 days | 110 (0.44) | 56 (0.6) | 54 (0.4) | 0.74 | 0.50–1.10 | 0.140 |
| 180 days | 175 (0.70) | 88 (0.9) | 87 (0.6) | 0.76 | 0.56–1.05 | 0.093 |
| Readmission | ||||||
| 30 days | 2819 (11.2) | 1210 (12.1) | 1609 (10.6) | 1.09 | 1.00–1.18 | <0.044 |
| 90 days | 3779 (15.0) | 1619 (16.2) | 2160 (14.2) | 1.08 | 1.00–1.16 | <0.042 |
| 180 days | 5190 (21.6) | 2199 (22.1) | 2989 (19.7) | 0.92 | 0.85–0.97 | <0.016 |
Preoperative group is reference; number of events (%) in group; LMWH = low-molecular-weight heparin; OR = odds ratio.