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. 2017 Aug 1;7:7036. doi: 10.1038/s41598-017-07389-0

Table 2.

Ultrasound and shear wave elastography characteristics of benign and malignant lesions.

Characteristic Overall Malignant Benign P-value
Patients 277 62 215
(22%) (78%)
Mean age (year) 45.1 ± 14.6 59.7 ± 12.8 40.9 ± 12.2 <0.001*
Lesions
 Diameter (mm) 15.6 ± 8.5 20.5 ± 9.5 14.2 ± 7.7 <0.001*
Shape <0.001*
 Oval/Round 158 12 146
(57.0%) (19.4%) (67.9%)
Irregular 119 50 69
(43.0%) (80.6%) (32.1%)
Lesion depth <0.001*
 >15mm 90 39 51
(32.5%) (62.9%) (23.7%)
 <15mm 187 23 164
(67.5%) (37.1%) (76.3%)
Orientation <0.001*
 Parallel 222 38 184
(80.1%) (61.3%) (85.6%)
 Not parallel 55 24 31
(19.9%) (38.7%) (14.4%)
Margin <0.001*
 Circumscribed 161 14 147
(58.1%) (22.6%) (68.4%)
 Non-circumscribed 116 48 68
(41.9%) (77.4%) (31.6%)
Posterior features <0.001*
 Changed 44 19 25
(15.9%) (30.6%) (11.6%)
 Unchanged 233 43 190
(84.1%) (69.4%) (88.4%)
Calcifications <0.001*
 Present 34 16 18
(12.3%) (25.8%) (8.4%)
 Absent 243 46 197
(87.7%) (74.2%) (91.6%)
Vascularity <0.001*
 Present 71 38 33
(25.6%) (61.3%) (15.3%)
Absent 206 24 182
(74.4%) (38.7%) (84.7%)
Echo pattern 0.314
 Hypoechoic 251 55 196
(90.6%) (88.7%) (91.2%)
 Isoechoic 11 2 9
(3.9%) (3.2%) (4.2%)
 Complex cystic 3 0 3
(1.1%) 0 (1.4%)
 Heterogeneous 12 5 7
(4.4%) (8.1%) (3.2%)
SWSSD (m/s) 0.74 ± 0.73 1.74 ± 0.81 0.45 ± 0.36 <0.001*
E-mean (kPa) 31.2 ± 26.9 62.2 ± 32.3 22.2 ± 16.9 <0.001*
ESD (kPa) 14.9 ± 16.1 36.9 ± 16.8 8.5 ± 8.3 <0.001*
SWS-mean (m/s) 2.91 ± 1.29 4.28 ± 1.51 2.51 ± 0.88 <0.001*

*Indicates a significant difference.

Data are shown as means ± standard deviations; SWSSD = standard deviation of shear wave speed; E-mean = the mean elasticity; ESD = standard deviation of elasticity; SWS-mean = the mean shear wave speed; Changed posterior features include enhancement, shadowing and combined pattern.