Table 8.
Cognition according to gender and APOE rs7412 in Chinese adults.
| Cognition ability | Male(n = 290) | Female(n = 624) | P-value | ||
|---|---|---|---|---|---|
| APOE rs7412 (C/C) (n = 243) | APOE rs7412 (C/T) (n = 47) | APOE rs7412 (C/C) (n = 529) | APOE rs7412 (C/T) (n = 95) | ||
| Visual and executive | 3.90 (3.71, 4.10) | 3.66 (3.16, 4.16) | 3.90 (3.76, 4.03) | 3.70 (3.31, 4.09) | 0.785 |
| Naming | 2.91 (2.84, 2.99) | 2.99 (2.81, 3.18) | 2.86 (2.81, 2.91) | 2.86 (2.71, 3.00) | 0.534 |
| Attention | 5.50 (5.32, 5.69) | 4.86 (4.37, 5.34) | 5.29 (5.16, 5.42) | 5.26 (4.87, 5.64) | 0.054 |
| Language | 2.23 (2.09, 2.37) | 1.77 (1.42, 2.12) | 2.17 (2.07, 2.26) | 2.25 (1.97, 2.53) | 0.026 |
| Abstraction | 1.75 (1.64, 1.87) | 1.72 (1.42, 2.01) | 1.57 (1.49, 1.65) | 1.51 (1.28, 1.74) | 0.967 |
| Memory and Delayed Recall | 2.93 (2.69, 3.17) | 2.51 (1.89, 3.12) | 3.12 (2.95, 3.28) | 2.72 (2.24, 3.21) | 0.987 |
| orientation | 5.77 (5.63, 5.90) | 5.58 (5.23, 5.93) | 5.72 (5.63, 5.82) | 5.77 (5.50, 6.05) | 0.293 |
| MoCA score | 25.32 (24.58, 26.07) | 23.47 (21.54, 25.39) | 24.87 (24.35, 25.39) | 24.32 (22.80, 25.84) | 0.274 |
Data were expressed as mean ± SE. General Line Model (GLM) was used for data analysis. Factors including age, BMI, education, smoking, alcohol drinking and physical activity levels were adjusted. P-value < 0.05 was considered as significance. ApoE, Apolipoprotein E.