Table 9.
Cognition according to gender and APOE rs429358 in Chinese adults.
| Cognition ability | Male (n = 290) | Female (n = 624) | P-value | ||
|---|---|---|---|---|---|
| ApoE rs429358 (T/T) (n = 234) | ApoE rs429358 (C/T) (n = 56) | ApoE rs429358 (T/T) (n = 526) | ApoE rs429358 (C/T) (n = 98) | ||
| Viso and executive | 4.00 (3.79, 4.21) | 3.57 (3.08, 4.06) | 3.79 (3.65, 3.93) | 3.80 (3.41, 4.20) | 0.172 |
| Naming | 2.97 (2.89, 3.05) | 2.94 (2.76, 3.12) | 2.88 (2.83, 2.93) | 2.83 (2.69, 2.98) | 0.900 |
| Attention | 5.51 (5.30, 5.71) | 4.85 (4.37, 5.33) | 5.20 (5.06, 5.33) | 5.35 (4.97, 5.73) | 0.013 |
| Language | 2.24 (2.09, 2.39) | 1.77 (1.42, 2.12) | 2.19 (2.09, 2.29) | 2.22 (1.95, 2.50) | 0.031 |
| Abstraction | 1.76 (1.63, 1.88) | 1.71 (1.42, 2.00) | 1.56 (1.48, 1.64) | 1.52 (1.28, 1.75) | 0.935 |
| Memory and delayed recall | 2.98 (2.72, 3.24) | 2.45 (1.84, 3.06) | 3.09 (2.92, 3.26) | 2.75 (2.27, 3.23) | 0.545 |
| orientation | 5.90 (5.75, 6.05) | 5.45 (5.10, 5.79) | 5.75 (5.66, 5.85) | 5.74 (5.46, 6.02) | 0.061 |
| MoCA score | 25.72 (24.90, 26.53) | 23.07 (21.18, 24.97) | 24.67 (24.13, 25.20) | 24.53 (23.01, 26.04) | 0.042 |
Data were expressed as mean ± SE. General Line Model (GLM) was used for data analysis. Factors including age, BMI, education, smoking, alcohol drinking and physical activity levels were adjusted. P-value < 0.05 was considered as significance. ApoE, Apolipoprotein E.