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. 2017 Aug 2;8:905. doi: 10.3389/fimmu.2017.00905

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Copyright © 2017 Liang, Liang, Hao, Lin, Wang, Wu, Jiang, Fu, Li, Ding, Liu, Xiong, Lai, Zhou, Chan and Hou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The apoptosis effect of root extract of Morinda officinalis (MORE) and hairy root extract of M. officinalis (MOHRE) on splenic T lymphocytes in dextran sodium sulfate (DSS)-induced chronic colitis mice. (A) The apoptosis of CD3⁺, CD4⁺, and CD8⁺ T cells was detected by Annexin V/PI staining. (B) The apoptosis ratio of CD3⁺ T cells. (C) The apoptosis ratio of CD3⁺CD4⁺ T cells. (D) The apoptosis ratio of CD3⁺CD8⁺ T cells. All data are expressed as mean ± SEM of three mice. *p < 0.05. ^**p < 0.01 vs. control group; ^#p < 0.05. ^##p < 0.01 vs. DSS group.